Analytical Challenges and Solutions in the Detection and Quantification of Food Allergens
Description:
Exposure to food allergens can cause serious, sometimes fatal, health consequences in consumers with food allergies. This population relies on accurate food labels to avoid exposure to their offending food allergen. However, undeclared allergens are still one of the main causes of food recalls in the US. To protect allergic consumers from undeclared food allergens, reliable analytical methods capable of detecting and quantifying multiple allergens in a variety of foods are needed. Immunochemical assays, such as lateral flow devices, ELISA, and xMAP, are the primary methods used for allergen testing due to their sensitivity and ease-of-use. Targeted liquid chromatography–tandem mass spectrometry (LC-MS/MS) methods are also in development as a multiplexed technique orthogonal to antibody-based methods. However, the method development community has recognized the need for harmonization and transparency especially with respect to method validation guidelines and reporting units. Fortunately, this harmonization has come at a time of recent major developments in the area of food allergens. Sesame has recently been added to the list of major allergens in the US through passage of the Food Allergy Safety, Treatment, Education, and Research (FASTER) Act in 2021. Additionally, the US Food and Drug Administration recently released a new draft guidance on food allergens. This symposium will cover the current state of affairs in the food allergen community including different issues and approaches to the detection and quantification of food allergens and gluten.
Alternate speakers: Michele Colgrave (CSIRO, Australia), Clare Mills (University of Manchester, UK), Linda Monaci (CNR, Italy), Rakhi Panda, Lauren Jackson, and Stefano Luccioli (US FDA)
Organizer: Katherine Fiedler - US Food and Drug Administration
Biography: Dr. Katherine Fiedler is currently a research chemist and acts as the food allergen research coordinator for the Spectroscopy and Mass Spectrometry Branch in the Center for Food Safety and Applied Nutrition at the US Food and Drug Administration (FDA). She received her B.Sc. in Chemistry from the University of Maryland Baltimore County and her Ph.D. in Chemistry from Johns Hopkins University under the direction of Dr. Robert J. Cotter. Dr. Fiedler joined the FDA in 2012 as a post-doctoral fellow and then in 2014 as a chemist in the Spectroscopy and Mass Spectrometry Branch. Her research primarily focuses on the development of mass spectrometric methods for the detection and quantification of food allergens and gluten.
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Katherine Fielder - US FDA
Melanie Downs - FARRP
Paul Wehling - ChemStats Consulting
Kate Rimmer - NIST
Michele Colgrave - CSIRO Agriculture and Food
Anne Eischeid - US FDA
Martin Chapman - InBio
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Analytical Challenges and Solutions in the Detection and Quantification of Food Allergens
Katherine Fiedler - US Food and Drug Administration
Single Lab Validation Experiments With Nested Factors
Paul Wehling - ChemStats Consulting
PCR-based Detection of Allergenic Foods
Anne Eischeid - US Food and Drug Administration
Progress on AOAC Guidance Documents for Gluten Method Validation
Laura Allred - Gluten Intolerance Group of North America
Feeding the world safely: Proteomics for allergen detection in common and novel foods
Michelle Colgrave - CSIRO
Mass Spectrometric Methods for Detection and Quantification of Food Allergens: Are We There Yet?
Melanie Downs - Food Allergy Research and Resource Program, University of Nebraska-Lincoln
Overview of current methods for food allergen and gluten analysis
Katherine Fiedler - US Food and Drug Administration
“Analytical Challenges and Solutions in the Detection and Quantification of Food Allergens” (Fiedler)
Catherine Rimmer - National Institute of Standards and Technology
Multiplex array technology (MARIA for Foods) for simultaneous detection and quantification of major allergens in foods
Martin Chapman - InBio
Analytical Challenges and Solutions in the Detection and Quantification of Food Allergens
Description
Session Number: O17-00
Session Type: Organized
Session Date: Tuesday 3/21/2023
Session Time: 1:30 PM - 4:45 PM
Room Number: 120C
Track: Food Science & Agriculture
Category: Food Science/Agriculture, Mass Spectrometry, Regulatory/Safety/Compliance
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